Hoping to capitalize upon the considerable public attention those pictures drew, Muybridge invented the Zoopraxiscope, a machine similar to the Zoetrope, but that projected the images so the public could see realistic motion. The system was, in many ways, a precursor to the development of the motion picture film. His presentations, in Europe and the United States, were widely acclaimed by both the public and specialist audiences of scientists and artists.
At the Chicago 1893 World's Columbian Exposition, Muybridge gave a series of lectures on the Science of Animal Locomotion in the Zoopraxographical Hall, built specially for that purpose in the "Midway Plaisance" arm of the exposition. He used his zoopraxiscope to show his moving pictures to a paying public making the Hall, the very first commercial movie theater.
At the University of Pennsylvania and the local zoo Muybridge used banks of cameras to photograph people and animals to study their movement. The models, either entirely nude or with as little clothing as a cache-sexe, were photographed in a variety of undertakings, ranging from boxing, to walking down stairs, to throwing water over one another and carrying buckets of water.
Eadweard Muybridge returned to his native England in 1894, published two further, popular books of his work, and died in Kingston upon Thames while living at the home of his cousin Catherine Smith, Park View, 2 Liverpool Road. The house has a British Film Institute commemorative plaque on the outside wall. Muybridge was cremated and his ashes interred at Woking.